Preclinical Evidence of Alzheimer Changes
نویسندگان
چکیده
منابع مشابه
Preclinical evidence of Alzheimer changes: convergent cerebrospinal fluid biomarker and fluorodeoxyglucose positron emission tomography findings.
BACKGROUND Alterations in cerebrospinal fluid (CSF) tau and beta-amyloid peptide 1-42 (Abeta(42)) levels and rates of cerebral glucose metabolism (CMRglu) on fluorodeoxyglucose positron emission tomography (FDG-PET) occur years before clinical symptoms of Alzheimer disease (AD) become manifest, but their relationship remains unclear. OBJECTIVE To determine whether CSF AD biomarker levels and ...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 2009
ISSN: 0003-9942
DOI: 10.1001/archneurol.2009.59